Best will always be remembered for becoming a pioneer in the English game after he overcame discrimination from the terraces and emerged as the first black striking hero.
The talented forward, who arrived from Bermuda back in 1969, enjoyed a memorable spell when he made 221 appearances for the east London Club and scored 58 goals.
Best was recently back in England and made his first visit to London Stadium for the games against Burnley and Hull and says it would have been a dream for him to play at the Hammers magnificent new home.
There have been some hurdles to overcome following the big move, but Best has no doubts that it will take the Club onto the next level and help West Ham challenge the elite clubs in the top flight.
Best said: “It is a magnificent new Stadium and just unbelievable. I would loved to have played in an arena like this. Words cannot explain how nice it looks and hopefully we can make it into a fortress.
“When I played I used to love playing in front of the big crowds and I am sure it is the same for the players now.
“When we used to play at the Boleyn Ground the support was fantastic and with 60,000 fans now inside London Stadium I am sure it will be just as good.
“The West Ham fans are among the best in the country and they can play a big part in helping the team to do well.
This is my club - I have got claret and blue blood. I consider this my second home.
Clyde Best
“I think West Ham will be able to compete with the big teams now and we need to concentrate on getting the job done.
“We proved last year that we could compete with the big teams and if we continue to show the same attitude we have got all the ability.”
The 65-year-old admits he will never forget the special relationship he built with the West Ham supporters during his eight-year spell and feels like he will always have a second home in the east end of London.
Best added: “I love being back in the east end of London. They like workers and will appreciate you if you give everything. They know their football and you cannot cheat them. You have to give them what they want because they deserve it.
“I played with Billy Bonds and I always used to watch him. He was getting applauded every time he touched the ball and it was because of his work ethic.
“I couldn't do what Billy did because he could run all day but I tried to follow that pattern and the fans appreciate that. For any young player, if you can look at someone like Billy Bonds you are on the right path and I tried to do the same.
“I faced some challenges but I was not going to let them stop me from what I wanted to do. Life is not easy with certain things.
“I thank my family and my mum and dad for the support they gave me. She always told me if you want to be treated properly, you treat people how you wanted to be treated and you cannot go wrong. That is how I try to live my life and I believe in that.
The Hammers got their season back on track with their biggest league victory at London Stadium last Saturday as they recorded an emphatic 3-0 win over Crystal Palace and Best sees no reason why they cannot enjoy a second half to the campaign and challenge in the top half of the table.
Best always enjoys coming back to England and says he always feels part of the family when he makes a return to east London and hopes to make many more visits to London Stadium in the future.
“This is my club - I have got claret and blue blood. When they lose I feel it just as much and it will always be that way. There is nothing like being in the east end of London. They are the greatest people around.
“I consider this my second home. The one thing about being in the east end is I can always see friends here and you cannot beat that.”