Jose Mourinho's Chelsea are the visitors to the Boleyn Ground this Wednesday as West Ham United look to get back to winning ways on home turf.
Here whufc.com takes a look at six memorable home wins for the Hammers over the Blues.
West Ham United 3-1 Chelsea
Premier League
1 December 2012
Just over two years ago the Hammers downed the European champions with a fine display at the Boleyn Ground
West Ham found themselves 1-0 down at the break to Juan Mata's goal, but came roaring back in the second period to silence the west Londoners.
Carlton Cole got the comeback started with a 63rd minute equaliser before late finishes from Mohamed Diame and Modibo Maiga set the seal on a triumphant Boleyn Ground afternoon.
West Ham United 1-0 Chelsea
Premier League
3 May 2003
Prior to that victory in 2012/13, West Ham's last home win over Chelsea came back in the final home game of the 2002/03 season.
The Hammers, under the temporary charge of Trevor Brooking, were deep in relegation danger but in the midst of a great run of form which gave them a chance of escaping.
Paolo Di Canio's 71st minute goal gave them the points and took the fight to the final day, but a 2-2 draw at Birmingham was not enough to save them, despite amassing 42 points.
West Ham United 2-1 Chelsea
Premier League
24 October 2001
All the goals came early on in this midweek meeting between the clubs, as West Ham emerged triumphant by the odd goal in three.
Just five minutes were on the clock when Michael Carrick gave the Hammers the lead, then Frederic Kanoute doubled the advantage eight minutes later.
Jimmy Floyd Hasselbaink got Chelsea back in it midway through the first half, but surprisingly that was where the scoring ended as the Hammers moved up to 14th in the table.
West Ham would eventually end the campaign in seventh, just one place behind their visitors.
West Ham United 3-2 Chelsea
Premier League
13 March 1997
This was a real see-saw battle, which both sides harboured ambitions of winning, until Paul Kitson struck late on to settle the matter.
Chelsea were first to edge in front through Gianluca Vialli in the 26th minute, but a Julian Dicks penalty ten minutes after half-time levelled things up.
Then it was West Ham's turn to lead as Kitson scored his first of the game, but Chelsea looked to have rescued a point when Mark Hughes notched three minutes from the end.
The Hammers were unbowed though and Kitson scored again to keep all three points in east London.
West Ham United 4-0 Chelsea
Division Two
14 February 1981
The Hammers were en route to promotion from Division Two when Chelsea came calling in February 1981.
The Blues had no answer to their hosts as the championship charge was comfortably maintained.
Trevor Brooking scored twice, while Alan Devonshire and David Cross were also on target as the west Londoners were overwhelmed.
West Ham topped the table from November onwards that season and ended up winning the title by a huge 13-point margin.
West Ham United 3-2 Chelsea
Division One
12 April 1965
Fresh from victory at Real Zaragoza in the first leg of their European Cup Winners' Cup semi-final, West Ham welcomed Chelsea to the Boleyn Ground and registered another win.
Geoff Hurst notched two of his 20 goals from that season, while John Sissons scored the other as the Hammers kept a grip on a top-ten position.
Ron Greenwood's men would go on to lift the Cup Winners' Cup, while also sealing a ninth-place league finish.