Tottenham Hotspur are the visitors to the Boleyn Ground for West Ham United's final home game of the 2013/14 Barclays Premier League season on Saturday.
The Hammers are seeking a third victory of the season against their London rivals after winning the reverse fixture 3-0 at White Hart Lane and knocking Spurs out of the Capital One Cup with a 2-1 win.
Here, whufc.com takes a look back at six memorable home victories against Tottenham.
West Ham United 1-0 Tottenham Hotspur
Barclays Premier League
25 September 2010
West Ham had Frederic Piquionne to thank as they picked up their first win of the season against Harry Redknapp's Tottenham.
The French striker headed home a Mark Noble corner to the delight of a packed Boleyn Ground.
The Hammers did however go on to suffer the ignominy of relegation later that season, finishing bottom of the table.
West Ham United 2-1 Tottenham Hotspur
Premier League
7 May 2006
Alan Pardew's Hammers crushed Tottenham's Champions League dream with a final day win which meant Spurs missed out on fourth place by two points.
Carl Fletcher's long range effort was cancelled out by old boy Jermain Defoe netting on his return to Upton Park before Yossi Benayoun scored a late winner.
Teddy Sheringham also had a penalty saved as the Hammers finished the season in a very respectable ninth place.
Carl Fletcher celebrates his goal against Spurs with Teddy Sheringham and Nigel Reo-Coker
West Ham United 2-0 Tottenham Hotspur
Premier League
1 March 2003
Les Ferdinand returned to haunt his former club and propel West Ham to a vital victory against their London rivals as their battle against relegation intensified.
The frontman had left Spurs for east London just a couple of months earlier and he notched his first goal for the Hammers against his old side with 31 minutes on the clock, with Kasey Keller unable to keep out his low shot.
Soon after the restart Keller was again picking the ball out of his own net as his fumble allowed Michael Carrick to put the Hammers two up.
More chances followed for the hosts, but they couldn't put more gloss on an already emphatic victory at the Boleyn Ground.
West Ham United 2-1 Tottenham Hotspur
Premier League
28 November 1998
Trevor Sinclair scored twice as the Hammers saw off Tottenham to rack up their fifth match without defeat in November 1998.
The wide man notched two of his seven goals during the 1998/99 season in this clash to inspire the home side to a rousing victory.
The Hammers enjoyed a fine season, finishing in fifth place in the top-flight while Spurs could only manage an eleventh place finish.
Trevor Sinclair wheels away in delight after scoring his first goal against Tottenham in 1998
West Ham United 4-3 Tottenham Hotspur
Premier League
24 February 1997
Julian Dicks was the hero as West Ham edged a seven goal thriller against Spurs at the Boleyn Ground.
The left-back scored twice, including one from the penalty spot, with further goals from Paul Kitson and John Hartson securing an exciting win.
Dicks finished the season as joint top-scorer with Kitson, both players having netted eight goals.
West Ham United 4-0 Tottenham Hotspur
Division One
8 February 1964
Four different goal scorers helped the Hammers inflict a crushing defeat on Tottenham at the Boleyn Ground back in 1964.
There were goals for Ronnie Boyce, Johnny Byrne, Geoff Hurst and John Sissons as the hosts ran riot in this London derby.
Victory helped make amends for a 3-0 loss at White Hart Lane earlier in a season which the Hammers would eventually finish 14th, ten places below Spurs.