Steve Potts' youngsters host Liverpool in the Barclays U18 Premier League at Little Heath on Saturday.
West Ham United's youth team have endured a difficult start to the season results-wise, failing to win any of their last five matches following a 2-1 opening-day victory over Manchester United.
The Hammers have been beaten by a single goal in all three of their away fixtures, while they have also drawn at home with Southampton and Blackburn Rovers in recent weeks.
Potts will likely name full-back Kyle Knoyle and centre-back Reece Burke in his starting XI. The pair were both on the substitutes' bench for the Development Squad in Friday's friendly with Ipswich Town and received call-ups to the England U18 squad for the first time last week.
Kick-off at Little Heath on Saturday is scheduled for 11am, with admission and parking both free of charge. If you cannot make it down in person, follow live twitter updates from @tommywathen.