Pablo Barrera will hope to help shoot Mexico through to the CONCACAF Gold Cup quarter-finals when El Tri take on Cuba on Thursday evening.
Mexico began their campaign with a comprehensive 5-0 win over El Salvador in Arlington, Texas, on Sunday.
With Cuba falling to defeat by the same scoreline at the hands of Costa Rica in their own opening Group A fixture, a Mexican victory on Wednesday combined with a Costa Rican win or draw against El Salvador would send Barrera and his compatriots through to the last-eight with a game to spare.
The West Ham United winger has been in impressive form for his country and is expected to start when the Mexicans lock horns with Cuba at the Bank of America Stadium in Charlotte, North Carolina.
With Manchester United striker Javier 'Chicarito' Hernandez, who netted a hat-trick against El Salvador, also at the top of his game, Mexico have been installed as the bookmakers' favourites to win the tournament for a record sixth time.