Team to face Palermo: Carroll; Spector, Collins, Gabbidon, Konchesky; Mascherano, Bowyer, Reo-Coker; Harewood, Cole, Tevez.
Substitutes: Green, Sheringham, Etherington, Benayoun, Mullins, Zamora, Ephraim.
Alan Pardew hands a debut to American defender Jonathan Spector, after Anton Ferdinand and Christian Dailly picked up injuries in the 2-0 defeat at Manchester City on Saturday.
James Collins has recovered from a slight groin injury to partner Danny Gabbidon in the centre of defence, while the Hammers boss has named an attacking 4-3-3 formation, with Marlon Harewood and Carlos Tevez supporting central striker Carlton Cole from the flanks.
Palermo team: Fontana, Cassani, Zaccardo, Barzagli, Pisano, Diana, Corini, Simplicio, Di Michele, Bresciano, Caracciolo.