"It was never a 3-0 game and we came off the pitch saying that," he says.
Looking back on the goals, Wayne says:
"The first one was a long ball over the top and striker has caught it really well.
"The second goal? I don't really know what happened; it was a free kick that has gone over the far side and come back in the box.
"The third was the one-two, and the whole thing is disappointing, because in the first half we were most definitely the better team - and we could have gone in 2-0 or 3-0 up comfortably.
"I don't think they had a chance in the first half.
"In the first half we had the better chances and even in the second half we had really good chances.
"But they have a top class keeper in van der Sar and he has done what he gets paid for.
"We felt comfortable going into the game; we thought we had a chance and we got at them from the off as we did at the start of the second half.
"We didn't get complacent but then we didn't do the right things at the sensible time and that cost us.
"But I don't think they got a shot on goal for a long time before Steve made three or four good saves, and then they got what from our point of view was a sloppy goal to give away."
Wayne was restored to the starting line-up in the absence of Jon Harley, who was ineligible, and he adds:
"It was nice to start and although we lost, on a purely personal point of view it was good to be out there again and playing.
"You miss it when you are not involved; I felt comfortable with my performance and felt I did okay.
"I got the ball quite a bit and feel we defended well until Christian went off, which was a major blow."
But Wayne does not see it as personal rivalry with Jon, though the pair, on short term contracts as they are at Upton Park, are effectively both playing for their futures.
"I am not like that; I go in there, when asked, to do my best," he says.
"I am sure the gaffer might make changes in the league but we will have to wait and see.
"Jon is a good lad and we get on really well so there is good competition.
"I am here to the end of the season and if I don't play, so be it, but I am still training hard and obviously playing for my future.
"If I don't play no one is going to get to see me but that is just the way it goes and we will have to wait and see what happens."
Wayne says the players will bounce back on Saturday, and adds:
"Hopefully no one will be despondent with the result and we will go into the Cardiff game and show the fans we can get back to winning ways.
"The gaffer said in there 'you can't get too down-hearted'; for 65 minutes we had the better team and created the better chances."