Youssef Sofiane returns to action after injury to play in the
reserve team's clash at Coventry City on Tuesday night.
Coventry, for their part, are hoping to build on a win at Leicester with some senior players in their side.
Richard Garcia is the only player with any first team experience involved for the Hammers, while David Forde plays only his third game for the second string.
Meanwhile, Izzie Iriekpen has extended his loan at third division Cambridge by a month.
Confirming the move, Peter Barnes says: "That will take him to the end of the season for them, unless Cambridge make the play-offs.
Team: Forde, McClenahan, Tattam, Lumsden, Delaney, Ward, Collington, McMahon, Sofiane, Garcia, M Cole. Subs (from): Blewitt, Jackson, Bunce, Pearson, Parrington, Wright.