West Ham United will kick-off their challenge on a fourth front by hosting Leeds United in the 2021/22 Emirates FA Cup third round.
The tie will take place at London Stadium over the weekend of Friday 7 until Monday 10 January 2022.
It is just the third time the two storied Premier League clubs have been drawn to face one another in the FA Cup, with Leeds prevailing 1-0 in a second-round replay in February 1924 and West Ham winning 4-1 in a fourth round tie in January 1930, with Vic Watson scoring all four goals.
The Irons reached the fifth round last season before being edged out 1-0 by Manchester United in extra-time on a bitterly cold night at Old Trafford.
West Ham, of course, are three-time winners of the FA Cup, lifting the trophy in 1964, 1975 and 1980, and also reached the final in 1923 and 2006.
However, the Hammers have not been past the quarter-finals since reaching that 2006 final, where they were beaten on penalties by Liverpool following a 3-3 draw at Cardiff's Millennium Stadium.
The way David Moyes' men have been performing in the Premier League, UEFA Europa League and EFL Cup this season, though, hopes will be high that we can go all the way in 2021/22.